Dr. Prasanta Banerji Homoeopathic Research Foundation

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Osteosarcoma

Osteosarcoma or bone cancer is a common type of childhood cancer. Recently, mortality rates due to Osteosarcoma has gone down. Severe pain is the major symptom of this disease. The affected bone may face fracture easily.

Osteosarcoma is the most common malignant bone tumor in youth. The average age at diagnosis is 15. Boys and girls have a similar incidence of this tumor until late adolescence, at which time boys are more commonly affected. The cause is not known. In some cases, osteosarcoma runs in families and at least one gene has been linked to increased risk. This gene is also associated with familial retinoblastoma, a cancer of the eye which occurs in children. It appears to be a defective tumor inhibitor gene.

Patient Information

Master MLMi aged 8 years was ill for 5 to 6 months when he first visited the clinic on 18th July 2003.
His chief complaints were swelling of left knee and difficulty in knee flexion. He did not have a history of any illnesses.

The initial observation from X-Ray of left knee dated 27.04.2003 was, "A large bony cyst with osteolytic lesion in metaphysis with sclerosis at edges of lower end of left femur."

A repeat X-Ray of left knee dated 05.06.2003 showed, " Well defined eccentric lesion in metaphysis with sclerosis at edges of lower end of left femur.? Bony Cyst."


osteocarcoma
X-Ray Dated 05.06.2003

The Histopathology (Site of biopsy – lower end of femur) report dated 12.06.2003 told "Diagnosis- Poorly differentiated sarcomatous lesion."

histopathology
Picture of Histopathology dated 12.06.2003

The observation during treatment from the X-Ray of left knee dated 16.12.2003 was " large osteolytic reaction noted in metaphysis of left femur with periosteal reaction." It revealed, "gross healing at osteolytic area."

osteocarcoma
X-Ray Dated 16.12.2003

Another X-Ray dated 14.08.2004 says, "Comparative study with that of previous skiagram dated 16.12.2003 reveals remineralisation seen at the lower 3rd of left femur." He had no complications during treatment.

osteocarcoma
X-Ray Dated 14.08.2004

It is concluded that a little boy came to our clinic on 18.07.2003 for the treatment of osteosarcoma at lower end of left femur confirmed by Histopathology Report dated 12.06.2003. The patient is now keeping all right and leading a trouble free life since last 2 years.

Patient Information

  • Name: Ms. S.S
  • Age: 33 years (on 27.07.2005)
  • Sex: Female
  • Duration of illness: 1½ months
  • Date of first visit: 27.07.2005
  • Chief complaints: Pain in and swelling in the right side of the shoulder since last 1½ months
  • Past history if any: Nil


Initial observations:
M.R.I. of shoulder done on 06.07.2005 “ A large expansile osteolytic mass is seen in metaphysis and part of greater tuberosity of right humerus. There is extension to the paraosteal soft tissues.
Bone scan done on 26.07.2005 – Increase uptake at right shoulder is compatible with increase osteogenic activity in the region. Rest of the skeletal tissue image morphology is within normal limits.
C.T. guided F.N.A. of the lytic lesion in the humerus done on 28.06.2005 – The overall cytomorphological features are of malignant tumour of messenchymal origin.
The possibility of soft tissue sarcoma like synovial sarcoma with secondary involvement of the bone has been favoured.
Review report of the above slide on 04.07.2005 by Chittaranjan National Cancer Institute – “Impression :- The features are of malignant mesenchymal tumour – Pleomorphic sarcoma possibility of primary bone tumour is to be considered.”
Observations during treatment:
X-Ray right shoulder done on 18.02.2006 – Much improvement is seen of the osteolytic lesion in the upper part of the right humerus.
X-Ray right shoulder done on 01.02.2007- Bone destruction at upper 3rd of right humerus with soft tissue swelling.
Complication during treatment if any: Nil
Summary:
33 years aged young gentle lady came to us from remote village of Bangladesh on 22.07.2005 presented with Pain in and swelling in the right side of the shoulder since last 1½ months. As per her initial observations, M.R.I. of shoulder done on 06.07.2005 “ A large expansile osteolytic mass is seen in metaphysis and part of greater tuberosity of right humerus. There is extension to the paraosteal soft tissues.
Bone scan dose on 26.07.2005 – Increase uptake at right shoulder is compatible with increase osteogenic activity in the region. Rest of the skeletal tissue image morphology is within normal limits.
C.T. guided F.N.A. of the lytic lesion in the humerus done on 28.06.2005 – The overall cytomorphological features are of malignant tumour of messenchymal origin.
The possibility of soft tissue sarcoma like synovial sarcoma with secondary involvement of the bone has been favoured.
Review report of the above slide on 04.07.2005 by Chittaranjan National Cancer Institute – “Impression :- The features are of malignant mesenchymal tumour – Pleomorphic sarcoma possibility of primary bone tumour is to be considered.” Clinically patient feels much better and no swelling and pain in right shoulder area after 8 – 9 months of our medication. During her treatment X-Ray right shoulder done on 18.02.2006 – Much improvement is seen of the osteolytic lesion in the upper part of the right humerus. Again X-Ray right shoulder done on 01.02.2007- Bone destruction at upper 3rd of right humerus with soft tissue swelling. Patient feels much better and continuing medicines for further improvement.
Visit dates:
27.07.2005; 23.08.2005; 07.11.2005; 10.03.2006; 24.07.2006; 14.11.2006; 01.02.2007; 19.02.2007; 09.04.2007; 16.04.2007.
Homeopathic Medicines used:

Symphytum 200c, two doses daily
Calcarea Phos 3X, two doses daily
Hypericum 200c, S.O.S for pain.